Nimesulide and Hepatotoxicity (Why This “Safe” NSAID Is Restricted or Banned in Many Countries)
Nimesulide, a commonly used NSAID, was once promoted as a stomach-friendly pain reliever. However, reports of unpredictable liver toxicity have led to its restriction or ban in many countries. Unlike other NSAIDs, liver injury from nimesulide can occur suddenly, even at standard doses, making monitoring unreliable. Safer alternatives like paracetamol, ibuprofen, and naproxen are preferred. This article explains why regulators worldwide limit nimesulide use, the risks involved, and practical guidance for safer pain management.
